The 38th Annual American Music Awards aired on 21 November, 2010. Below are a list of the winners, notice how they don't use "Best" but "Favorite" when describing the categories:

• Artist of the Year – Justin Bieber
• Favorite Album – My World 2.0 – Justin Bieber
• Favorite Alternative Rock Artist – Muse
• Favorite Adult Contemporary Artist – Michael Buble
• Favorite Contemporary Inspirational Artist – MercyMe
• Favorite Country Album – Play On – Carrie Underwood
• Favorite Country Band/Duo/Group – Lady Antebellum
• Favorite Country Female Artist – Taylor Swift
• Favorite Country Male Artist – Brad Paisley
• Favorite Latin Artist – Shakira
• Favorite Pop/Rock Band/Duo/Group – The Black Eyed Peas
• Favorite Pop/Rock Female Artist – Lady Gaga
• Favorite Pop/Rock Male Artist – Justin Bieber
• Favorite Rap/Hip-Hop Album – Recovery – Eminem
• Favorite Rap/Hip-Hop Male Artist – Eminem
• Favorite Soul/R&B Album – Raymond v. Raymond - Usher
• Favorite Soul/R&B Female Artist – Rihanna
• Favorite Soul/R&B Male Artist – Usher
• Favorite Soundtrack – Glee: The Music, Volume 3 Showstoppers - Glee cast
• T-Mobile Breakthrough Artist – Justin Bieber

Jamiroquai's Traveling Without Moving & A Funk Odyssey, Kem's Kemistry & Kindred's Surrender To Love have been updated.